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What is the main role of Mg2+ in the body?


A) Muscle contraction
B) Nerve impulse
C) Blood clotting
D) Cofactors for intracellular enzymes

E) B) and D)
F) All of the above

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Most of the Ca2+ in the body is in the ________.


A) bones
B) plasma
C) kidneys
D) GI tract
E) extracellular fluid

F) D) and E)
G) B) and D)

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Which of the following is NOT a principle sensor for thirst regulation?


A) Osmoreceptors in the hypothalamus
B) Arterial baroreceptors
C) Juxtaglomerular apparatus
D) Mouth mucosa

E) A) and C)
F) C) and D)

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Which of the following would be expected to cause hyponatremia?


A) High intake of Na+
B) Increased aldosterone production
C) Increased urine output
D) Decreased aldosterone production
E) Decreased ADH production

F) B) and E)
G) A) and C)

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Which of the following is not a function of the carbonic acid/bicarbonate system?


A) Regulation of the pH of the intracellular environment.
B) Regulating pH changes of the blood during exercise.
C) Regulation of blood pH during elevated fat metabolism.
D) Regulation of blood pH in coordination with the respiratory system.
E) Regulation of blood pH in coordination with the kidneys.

F) All of the above
G) A) and C)

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Loss of a large volume of sweat will


A) decrease the hematocrit.
B) decrease ADH production.
C) increase the blood pressure.
D) increase the osmolality of body fluids.
E) decrease the osmolality of body fluids.

F) C) and E)
G) B) and D)

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Parathyroid hormone affects the ________.


A) bones, heart, and blood
B) kidney, liver, and spleen
C) intestine, kidneys, and bone
D) liver, stomach, and small intestine
E) stomach, pancreas, and bone

F) B) and D)
G) A) and B)

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Acetazolamide (Diamox) is a diuretic that functions by blocking the activity of carbonic anhydrase inside kidney tubule cells. This slows the formation of carbonic acid, which slows H+ the formation in the cells and Na+ reabsorption at the tubule. This results in the diuretic effect. Select from the following list the possible side-effects of Azetazolamide. (1) Acidosis (2) Reduced movement of bicarbonate ion into the plasma (3) An alkaline urine is produced (4) Respiration increases


A) 1, 4
B) 2, 3
C) 1, 2, 3
D) 2, 3, 4
E) 1, 2, 3, 4

F) A) and C)
G) A) and B)

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The major route of excretion for Na+ (under normal conditions) is the ________.


A) skin
B) kidney
C) GI tract
D) adrenal cortex
E) sweat

F) B) and E)
G) A) and B)

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Respiratory alkalosis can occur as a result of ________.


A) asphyxia
B) asthma
C) severe emphysema
D) hyperventilation
E) hypoventilation

F) A) and C)
G) D) and E)

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The cation that plays a major role in determining the osmotic pressure of the plasma is ________.


A) Na+
B) K+
C) Cl−
D) phosphate
E) H+

F) B) and C)
G) A) and B)

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Which of the following terms does not belong with the other three?


A) Acidosis
B) pH increases
C) H+ concentration increases
D) Carbonic acid levels increase
E) pH decreases

F) B) and D)
G) A) and E)

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What roles does phosphate play in the body?


A) It is found in the salts of bone and teeth.
B) It is an important component of several macromolecules.
C) It affects neuromuscular activity.
D) It is part of an important intracellular buffer system.
E) It affects the action of the sodium-potassium pump.

F) A) and B)
G) A) and C)

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Which of the following substances releases H+ into a solution?


A) Acids
B) Bases
C) Salts
D) Glucose
E) Water

F) A) and D)
G) A) and C)

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Hyposecretion of aldosterone would lead to


A) increased secretion of H+.
B) decreased secretion of H+.
C) no change in secretion of H+.

D) All of the above
E) B) and C)

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Parathyroid hormone increases the activity of ________ in bone and increases the rate of Ca2+ ________ in the kidney tubules.


A) osteoclast; reabsorption
B) osteoblast; reabsorption
C) osteocyte; reabsorption
D) osteocyte; secretion
E) osteoblast; secretion

F) B) and C)
G) C) and D)

Correct Answer

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Decreased extracellular K+ levels cause


A) cells to become more excitable.
B) hyperpolarization of plasma membranes.
C) more action potentials to be generated.
D) increased permeability of plasma membranes.
E) hypopolarization of plasma membranes.

F) A) and B)
G) A) and C)

Correct Answer

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The predominant intracellular cation is ________.


A) K+
B) Na+
C) Ca2+
D) Mg2+
E) Cl−

F) A) and E)
G) A) and B)

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The most common cause of hyperkalemia is ________.


A) vomiting
B) increased dietary intake
C) increased urinary output
D) cellular injury or death
E) diarrhea

F) A) and E)
G) A) and B)

Correct Answer

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Where is the highest concentration of bicarbonate ion found?


A) Plasma
B) Intracellular fluid
C) Interstitial fluid
D) Lymph

E) None of the above
F) A) and C)

Correct Answer

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