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The ion primarily responsible for depolarization in pacemaker cells is ________, whereas the ion primarily responsible for this in other cardiac cells is ________.


A) Na+; Ca2+
B) Ca2+; Na+
C) K+; Na+
D) Ca2+; K+

E) B) and C)
F) A) and D)

Correct Answer

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Which of the following is a feature shared by cardiac muscle and skeletal muscle?


A) Muscle fiber striations
B) Dependence upon nervous stimulation
C) Communication via electrical (gap) junctions
D) Intercalated discs
E) Autorhythmicity

F) A) and E)
G) C) and E)

Correct Answer

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Why is body temperature sometimes reduced during heart surgery?


A) To slow respiration
B) To increase heart rate
C) To decrease heart rate
D) To increase the oxygen content of blood

E) All of the above
F) C) and D)

Correct Answer

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Under resting conditions, the normal stroke volume is approximately ________.


A) 55 mL
B) 70 mL
C) 110 mL
D) 125 mL
E) 180 mL

F) A) and D)
G) B) and D)

Correct Answer

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The chamber of the heart that endures the highest pressure is the


A) right atrium.
B) left atrium.
C) right ventricle.
D) left ventricle.
E) coronary sinus.

F) B) and E)
G) A) and B)

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Identify the structures that contribute to the slow onset of contraction and prolonged contraction phase in cardiac muscle tissue.


A) Desmosomes
B) Gap junctions
C) Intercalated discs
D) T-tubules
E) Terminal cisternae

F) A) and C)
G) A) and D)

Correct Answer

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Which of the following is a function of the heart skeleton?


A) Provides electrical insulation between the atria and ventricles
B) Supplies support and reinforcement for the valves
C) Provides a rigid site for cardiac muscle attachment
D) All of the choices are functions of the heart skeleton.

E) None of the above
F) All of the above

Correct Answer

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Calcium-induced calcium release occurs when


A) Ca2+ from the sarcoplasmic reticulum stimulates the movement of Ca2+ into the cell through the plasma membrane.
B) Ca2+ is released from both the sarcoplasmic reticulum and the cardiac muscle cell.
C) the eflux of Ca2+ from the cell results in depolarization.
D) Ca2+ entering through the plasma membrane stimulates release of Ca2+ from the sarcoplasmic reticulum.

E) B) and C)
F) A) and C)

Correct Answer

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Which statement accurately describes a condition of the heart chambers during the cardiac cycle?


A) The right atrium and the right ventricle contract simultaneously.
B) The left atrium contracts before the right atrium.
C) All four chambers of the heart contract at the same time.
D) All four chambers of the heart are in diastole at the same time.

E) A) and D)
F) A) and C)

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The spontaneous opening of Na+ channels marks the beginning of ________ of a cardiac muscle cell.


A) depolarization
B) repolarization
C) hyperpolarization
D) isopolarization
E) afterpolarization

F) A) and D)
G) A) and C)

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The tricuspid valve is closed


A) during active filling of the ventricles.
B) when the mitral valve is open.
C) while the atria are contracting.
D) during ejection.
E) during passive filling of the ventricles.

F) All of the above
G) A) and C)

Correct Answer

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The "pacemaker" of the heart is the


A) right bundle branch.
B) left bundle branch.
C) AV node.
D) SA node.
E) PM node.

F) A) and D)
G) B) and E)

Correct Answer

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The pericardial sac is lined with


A) fibrous pericardium.
B) parietal pericardium.
C) visceral pericardium.
D) myocardium.
E) epicardium.

F) A) and B)
G) A) and C)

Correct Answer

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The long refractory period observed in cardiac muscle


A) prolongs depolarization of the cardiac muscle.
B) prevents tetanic contractions of the cardiac muscle.
C) ensures that the heart has adequate time to contract.
D) prevents the heart rate from slowing down.
E) prevents an increase in heart rate.

F) A) and E)
G) C) and E)

Correct Answer

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Calcium channel blockers are frequently used to


A) increase the heart rate.
B) treat tachycardia or other arrhythmias.
C) speed up conduction of impulses through the AV node.
D) slow the closing of K+ channels.
E) treat bradycardia and low blood pressure.

F) B) and E)
G) A) and B)

Correct Answer

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Coronary artery disease can diminish myocardial blood flow resulting in the death of myocardial cells. This condition is known as a myocardial ________.


A) attack
B) angina
C) necrosis
D) cirrhosis
E) infarction

F) A) and B)
G) C) and D)

Correct Answer

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Which of the following events occurs first?


A) Threshold
B) Depolarization
C) Early repolarization
D) Final repolarization
E) Pacemaker potential

F) A) and D)
G) D) and E)

Correct Answer

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Ventricular contraction begins at the


A) AV bundle.
B) apex of the heart.
C) base of the heart.
D) superior portion of the interventricular septum.
E) top of the ventricles.

F) All of the above
G) C) and E)

Correct Answer

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Which of the following phrases would apply to cardiac muscle cells?


A) Organized in parallel columns or bundles
B) Contain actin but no myosin
C) Develop a significant oxygen deficit during systole
D) Multinucleated like skeletal muscle fibers
E) Possess special cell-to-cell contacts called intercalated discs

F) C) and D)
G) B) and C)

Correct Answer

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After entering the right atrium, the furthest a red blood cell can travel is the ________.


A) right ventricle
B) pulmonary trunk
C) superior vena cava
D) ascending aorta
E) left atrium

F) All of the above
G) A) and C)

Correct Answer

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