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The release of chemicals from an endocrine or exocrine gland is referred to as ______.


A) Absorption
B) Diffusion
C) Filtration
D) Secretion

E) All of the above
F) B) and D)

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Which pattern of hormone secretion, represented by epinephrine, can have dramatic changes in its concentration and circulating levels?


A) chronic hormone secretion
B) long-term hormone secretion
C) episodic hormone secretion
D) acute hormone secretion

E) B) and D)
F) B) and C)

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Members of which group of hormones are made from cholesterol?


A) amino acid derivatives
B) peptides
C) proteins
D) steroids

E) B) and C)
F) None of the above

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Match the description with the type of receptor model. -intracellular mediator


A) nuclear receptor model
B) membrane-bound receptor model

C) A) and B)
D) undefined

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Sympathetic neurons can serve as ______ stimuli for hormone release from certain endocrine organs.


A) Autocrine
B) Humoral
C) Paracrine
D) Neural

E) None of the above
F) All of the above

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The length of time needed to eliminate half of a dose of a hormone is called its _______ ________.

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Once a lipid-soluble hormone is conjugated in the liver


A) its half-life is increased.
B) it can be more quickly eliminated from the body.
C) it can be stored for later use.
D) it is actively transported into cells.
E) it is more slowly eliminated from the body.

F) D) and E)
G) C) and E)

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Match the chemical signal with the appropriate description. -autocrine


A) chemicals produced by neurons that function as hormones
B) chemicals that act locally on nearby cells
C) chemical secreted by presynaptic terminal
D) influences same cell type from which it is secreted
E) chemical secreted into blood by specialized cells; travels some distance to target tissues

F) A) and E)
G) C) and E)

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The endocrine system


A) releases neurotransmitters into ducts.
B) secretes chemicals that reach their targets through the bloodstream.
C) communicates via frequency-modulated signals.
D) contains organs called exocrine glands.
E) is isolated from the nervous system.

F) A) and E)
G) D) and E)

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Which of the following statements is NOT true?


A) The hypothalamus is important to both the nervous and endocrine systems.
B) Both the nervous and endocrine systems may utilize the same chemical molecule.
C) Some neurons secrete hormones.
D) Both the nervous and endocrine systems respond quickly and are active for a long time.

E) B) and C)
F) A) and C)

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Up-regulation


A) results in a decrease in the number of receptor sites in the target cell.
B) produces an increase in the sensitivity of the target cell to the hormone.
C) is found in target cells that maintain a constant level of receptors.
D) produces insensitivity to the hormone in the target tissue.
E) moves the receptors up on the membrane.

F) A) and B)
G) All of the above

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Secretion of the hormones ___________ and ____________ exemplify the pattern of chronic hormone secretion.


A) epinephrine and norepinephrine
B) insulin and glucagon
C) calcitonin and PTH
D) estrogen and progesterone
E) thyrotropin and thyroxine

F) A) and B)
G) None of the above

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Hormones are intercellular chemical signals that


A) are secreted into the external environment where they act.
B) affect only non-hormone producing organs or tissues.
C) help coordinate growth, development and reproduction.
D) operate primarily by positive feedback.

E) A) and D)
F) C) and D)

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Match the description with the type of receptor model. -generally observe a latent period


A) nuclear receptor model
B) membrane-bound receptor model

C) A) and B)
D) undefined

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Match the description with the type of receptor model. -G-protein


A) nuclear receptor model
B) membrane-bound receptor model

C) A) and B)
D) undefined

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Which pattern of hormone secretion, often observed in steroid reproductive hormones, will fluctuate over a monthly cycle?


A) acute hormone secretion
B) episodic hormone secretion
C) long-term hormone secretion
D) chronic hormone secretion

E) B) and C)
F) All of the above

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Most hormones are regulated by


A) negative-feedback mechanisms.
B) neural-feedback mechanisms.
C) positive-feedback mechanisms.
D) hormonal-feedback mechanisms.

E) A) and D)
F) B) and C)

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Thyroid hormones (TH) normally travel in the blood both free and bound to TH-binding proteins. What would you expect to see in the blood work of a patient who had a deficiency of TH-binding protein?


A) Normal free TH levels, and low bound TH levels.
B) Low free TH levels, and low bound TH levels.
C) Low free TH levels, and normal bound TH levels.
D) Normal free TH levels, and normal bound TH levels.

E) All of the above
F) A) and B)

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Match the chemical signal with the appropriate description. -endocrine


A) chemicals produced by neurons that function as hormones
B) chemicals that act locally on nearby cells
C) chemical secreted by presynaptic terminal
D) influences same cell type from which it is secreted
E) chemical secreted into blood by specialized cells; travels some distance to target tissues

F) C) and E)
G) B) and D)

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Arrange the following events in proper sequence: (1) The activating hormone interacts with a membrane-bound receptor. (2) Cyclic AMP causes the cell to carry out a function characteristic for that specific hormone. (3) Adenylyl cyclase catalyzes the transformation of ATP to cyclic AMP. (4) Adenylyl cyclase is activated.


A) 1, 2, 3, 4
B) 1, 4, 3, 2
C) 3, 4, 2, 1
D) 1, 3, 2, 4
E) 1, 3, 4, 2

F) A) and E)
G) A) and D)

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