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Long bones grow in length at the


A) endosteum-periosteum junction.
B) articular cartilage.
C) center of the shaft.
D) center of the epiphysis.
E) epiphyseal plate.

F) A) and E)
G) All of the above

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What is the type of ossification that forms the flat bones of the skull?


A) intramembranous ossification
B) endochondral ossification

C) A) and B)
D) undefined

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The zygomatic bone is an example of a(n)


A) long bone.
B) flat bone.
C) short bone.
D) irregular bone.

E) C) and D)
F) B) and C)

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Spongy bone tissue


A) contains interconnecting plates called trabeculae.
B) is very dense.
C) contains concentric lamellae.
D) is the primary component of compact bone.
E) has many spaces and lacks osteocytes.

F) A) and B)
G) A) and C)

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Which of the following cell types is responsible for breaking down bone matrix?


A) osteoclast
B) fibroblast
C) osteocyte
D) chondroclast
E) chondroblast

F) All of the above
G) A) and B)

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What does structure "C" represent on the bone diagram?


A) epiphysis
B) epiphyseal lines
C) cancellous bone
D) articular cartilage
E) diaphysis

F) A) and D)
G) A) and E)

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Which of the following statements about bone growth is TRUE?


A) Most growth in long bones results from interstitial growth.
B) In the epiphyseal plate, osteoblasts degenerate to form chondrocytes.
C) Endochondral growth in long bones occurs at the epiphyseal plate.
D) Bones can not grow by appositional growth.
E) Appositional bone growth results in increased bone length.

F) C) and E)
G) All of the above

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Cartilage


A) is surrounded by a membrane called the periosteum.
B) is composed of osteons.
C) is well vascularized.
D) contains chondrocytes located in lacunae.
E) does not need nutrients and oxygen so it has no blood vessels.

F) A) and E)
G) None of the above

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What type of tissue covers the ends of long bones?


A) articular cartilage
B) fibrocartilage
C) cancellous bone
D) elastic cartilage
E) periosteum

F) C) and D)
G) B) and E)

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Osteoporosis is


A) bone inflammation that often results from bacterial infection.
B) a disease in adults characterized by softening of bones resulting from calcium depletion.
C) a group of genetic disorders producing very brittle bones that are easily fractured; occurs because of insufficient collagen development.
D) a disease in adults, especially women, characterized by a reduced amount of bone matrix.
E) a disease in children characterized by soft, bowed, and swollen bones.

F) C) and D)
G) D) and E)

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The compression (weight-bearing) strength of bone matrix is due to the presence of


A) hydroxyapatite crystals.
B) collagenase.
C) collagen fibers.
D) elastin fibers.
E) bone marrow.

F) All of the above
G) C) and D)

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Intramembranous ossification


A) occurs when osteoblasts invade the spaces left by dying cartilage cells.
B) forms the bones of the roof of the skull.
C) occurs on the outer surface of the membrane.
D) is the process that produces most of the skeletal system.
E) occurs when bones develop from cartilage models.

F) A) and E)
G) C) and D)

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An X-ray determines that Peter fractured the shaft of his humerus. The break is in the _____________ of the bone.


A) diaphysis
B) epiphyseal line
C) articular surface
D) epiphysis
E) growth plate

F) A) and B)
G) B) and D)

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Collagen and calcium hydroxyapatite are the primary constituents of


A) bone matrix.
B) blood.
C) fibrous cartilage.
D) hyaline cartilage.
E) ligaments.

F) B) and C)
G) A) and E)

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Osteomyelitis causes destruction of bone tissue primarily by


A) promoting inflammation and overstimulation of osteoclast activity.
B) inhibiting bone marrow production of osteoclasts.
C) suppressing the production of RANKL by osteoblasts.
D) stimulating apoptosis in osteoclast cells.

E) A) and B)
F) A) and C)

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This is a diagram of calcium homeostasis. What process is represented by "C"?


A) Calcium is lost in urine.
B) PTH promotes calcium release into blood by osteoclast.
C) Vitamin D promotes calcium absorption.
D) Calcium is removed from blood by osteoblasts.
E) PTH promotes calcium reabsorption from urine.

F) A) and D)
G) A) and E)

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The type of cartilage associated with bone function and development is


A) osteocartilage.
B) elastic cartilage.
C) hyaline cartilage.
D) interstitial cartilage.
E) fibrocartilage.

F) A) and C)
G) B) and E)

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Which of the following statements regarding calcium homeostasis is true?


A) When blood calcium levels are too low, osteoclast activity increases.
B) Parathyroid hormone increases calcium loss from the kidney.
C) Increased osteoblast activity increases blood calcium levels.
D) Calcitonin elevates blood calcium levels.
E) Parathyroid hormone inhibits osteoclast activity.

F) B) and E)
G) B) and D)

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Appositional growth deposits a new layer of bone


A) in the epiphyseal plate of long bones.
B) in the secondary ossification center of the epiphyses.
C) on the surface of the bone.
D) on cancellous, but not compact bone.
E) in interstitial areas.

F) All of the above
G) C) and E)

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This is a diagram of calcium homeostasis. What process is represented by "B"?


A) Calcium is lost in urine.
B) Calcium is removed from blood by osteoblasts.
C) PTH promotes calcium reabsorption from urine.
D) Vitamin D promotes calcium absorption.
E) PTH promotes calcium release into blood by osteoclast.

F) D) and E)
G) A) and D)

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