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Which of the following membranes covers the surface of a mature bone?


A) perichondrium
B) perimysium
C) periosteum
D) peritendineum
E) peritoneum

F) A) and E)
G) D) and E)

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What structure forms between the ends of a broken bone and also the marrow cavities?


A) external callus
B) compact bone
C) internal callus
D) hematoma

E) A) and D)
F) All of the above

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When a fracture begins to heal, one type of bone cell moves into the fracture site and tears down the damaged bone tissue. Which of the following does this?


A) osteoblasts
B) osteocytes
C) osteoclasts
D) osteons
E) matrix cells

F) D) and E)
G) B) and E)

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Canaliculi are found in this type of bone tissue.


A) compact bone
B) both spongy and compact
C) spongy bone

D) B) and C)
E) All of the above

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Calcitonin


A) decreases osteoblast activity.
B) is associated with decreased osteoclast activity.
C) decreases osteochondral progenitor cell activity.
D) decreases osteocyte activity.
E) has no effect on bone cells.

F) C) and D)
G) A) and D)

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The ethmoid and sphenoid bones are formed by ___________


A) intramembranous ossification
B) endochondral ossification

C) A) and B)
D) undefined

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Brittle bone disorder is another name for


A) scurvy.
B) osteomyelitis.
C) osteoporosis.
D) osteomalacia.
E) osteogenesis imperfecta.

F) A) and E)
G) None of the above

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The covering of the outer surface of bone is the


A) trabeculae.
B) lamellae.
C) lacunae.
D) periosteum.
E) canaliculi.

F) C) and D)
G) A) and E)

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The stem cells of osteoclasts are


A) osteocytes.
B) chondrocytes.
C) monocytes.
D) osteochondral progenitor cells.
E) osteoclasts.

F) B) and C)
G) A) and C)

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Which type of bone cells give rise to osteoblasts?


A) osteochondral progenitor cell
B) osteoblasts
C) osteoclasts
D) osteocytes

E) C) and D)
F) A) and B)

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How does the respiratory system contribute to osteoporosis?


A) Calcium ions released from the bones are excreted.
B) Decreased estrogen levels following menopause contribute to the disease.
C) Lack of exposure to sunlight reduces vitamin D production and decreases calcium absorption.
D) Immune cells resist infections and release chemicals that promote tissue repair.
E) Excessive smoking lowers estrogen levels, which increases bone loss.

F) B) and C)
G) None of the above

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Osteoblasts involved in bone growth in length come primarily from


A) chondrocytes.
B) connective tissue surrounding blood vessels from the endosteum.
C) osteocytes.
D) periosteum.
E) endothelium of blood vessels.

F) A) and B)
G) B) and C)

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Which type of bone cells lie in lacunae?


A) osteocytes
B) osteoblasts
C) osteoclasts
D) osteochondral progenitor cell

E) A) and B)
F) A) and C)

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Osteomalacia is


A) a disease in adults characterized by softening of bones resulting from calcium depletion.
B) bone inflammation that often results from bacterial infection.
C) a disease in children characterized by soft, bowed, and swollen bones.
D) a disease in adults, especially women, characterized by a reduced amount of bone matrix.
E) a group of genetic disorders producing very brittle bones that are easily fractured; occurs because of insufficient collagen development.

F) B) and D)
G) C) and D)

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In which of the following locations in a growing bone would the greatest osteoclast activity be found?


A) articular cartilage
B) perichondrium
C) epiphyseal plate
D) epiphysis
E) medullary cavity

F) A) and E)
G) A) and C)

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The type of lamellae that forms the outside surface of compact bone is


A) interstitial.
B) circumferential.
C) appositional.
D) concentric.
E) oppositional.

F) A) and D)
G) A) and E)

Correct Answer

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Parathyroid hormone (PTH) causes


A) increased RANKL and decreased OPG.
B) PTH has no effect on RANKL and OPG.
C) increased RANKL and increased OPG.
D) decreased RANKL and decreased OPG.
E) decreased RANKL and increased OPG.

F) None of the above
G) B) and E)

Correct Answer

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How does the digestive system contribute to osteoporosis?


A) inadequate amounts of calcium and vitamin D in the diet
B) lack of exercise reduces muscle stress on bone
C) calcitonin is used to treat osteoporosis
D) pain following injury helps prevent further injury
E) blood clotting starts repair process

F) C) and D)
G) B) and C)

Correct Answer

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The type of lamellae found between osteons (Haversian systems) is


A) interstitial.
B) oppositional.
C) appositional.
D) circumferential.
E) concentric.

F) C) and D)
G) A) and B)

Correct Answer

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Bone growth at the articular cartilage is responsible for bone growth of


A) long bones.
B) only the cartilage.
C) flat bones.
D) short bones.
E) irregular bones.

F) A) and E)
G) A) and B)

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