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If the signal molecule acts on the cell that secreted it, the chemical is called a(n)________.

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Explain how epinephrine can cause intestinal blood vessels to constrict and cause skeletal muscle blood vessels to dilate.

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Epinephrine can bind to differ...

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The most important factor determining which type of receptor a signal molecule will bind to is


A) the lipid solubility of the ligand.
B) the size of the ligand.
C) the size of the receptor molecule.
D) the location of the receptor molecule.

E) All of the above
F) C) and D)

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Nobel Prizes were awarded to the discoverers of G proteins, the G protein-coupled adenylyl cyclase-cAMP system, and nitric oxide.Summarize each of these, and explain the importance of these discoveries to our understanding of signal pathways.

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G proteins are coupled to hundreds of di...

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Compare and contrast neural, neuroendocrine, and endocrine reflex pathways.

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See Table ...

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Homeostatic control that takes place at the tissue or cell by using paracrine or autocrine signals is called


A) local control.
B) reflex control.
C) Cannon's law.
D) down-regulation.

E) All of the above
F) None of the above

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Second messenger molecules directly


A) change the regulation of ion channels.
B) increase intracellular calcium concentration.
C) change enzyme activity.
D) change regulation of gene expression.
E) All of the answers are correct.

F) A) and C)
G) C) and D)

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Diacylglycerol is produced from


A) cyclic AMP.
B) phospholipase C.
C) a G protein.
D) protein kinase A.
E) phosphatidylinositol bisphosphate.

F) None of the above
G) A) and C)

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Most long-distance communication between cells takes place through the ________ and ________ systems with their combination of chemical and electrical signals.

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Signal molecule receptors exhibit


A) specificity only.
B) competition only.
C) saturation only.
D) competition and saturation only.
E) specificity, competition, and saturation.

F) A) and C)
G) A) and D)

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Before nitric oxide was identified, its action was observed in ________ and it was given the name ________.

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endothelial cells (b...

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One intracellular calcium-binding protein is


A) calmodulin.
B) calcitonin.
C) calcitriol.
D) IP₃.
E) nitric oxide.

F) B) and E)
G) A) and D)

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In your own words restate and explain Cannon's four postulates for maintaining homeostasis.

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This is discussed in...

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Describe the signal molecule derivatives of arachidonic acid.

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Leukotrienes are secreted by certain typ...

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Which of the following are considered differences between endocrine and neural control systems?


A) specificity
B) nature of the signal
C) speed
D) duration of action
E) All of the answers are correct.

F) C) and D)
G) A) and D)

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________ is a process by which an extracellular signal molecule, called the ________, activates a membrane receptor that in turn alters intracellular molecules, called the ________, to create a response.

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Signal transduction,...

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________ are molecules that bind to the receptor in such a way that they block the normal ligand from binding and turning the receptor on.As a result, the signal pathway remains inactive.

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Antagonist...

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The intracellular effector in chemical signaling is often


A) a hormone.
B) a membrane receptor molecule.
C) ATP.
D) a protein kinase.
E) cholesterol.

F) A) and E)
G) A) and B)

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Briefly explain the effects of the hormone insulin on glucose transport.What is diabetes mellitus? How are types I and II different? Why do insulin injections help alleviate one type but not the other?

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Insulin promotes glucose transport into ...

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Match the term with its description: -receives information about the regulated variable and initiates a response


A) threshold
B) effector
C) integrating center
D) setpoint
E) sensory receptor

F) B) and D)
G) None of the above

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