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Stem cells that will form B cells or NK cells are found only in the


A) red bone marrow.
B) liver.
C) spleen.
D) thymus.
E) kidneys.

F) All of the above
G) C) and D)

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The process by which antibodies bind to antigenic sites on viruses or toxins, rendering them incapableofbinding to other cells, is called


A) opsonization.
B) activation.
C) agglutination.
D) precipitation.
E) neutralization.

F) C) and D)
G) All of the above

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Compared to blood capillaries, lymph capillaries exhibit all of the following except that they


A) have no basement membrane.
B) have only a tunica interna.
C) have walls of endothelial cells that overlap like shingles.
D) are smaller in diameter.
E) are frequently irregular in shape.

F) A) and E)
G) None of the above

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The various classes of immunoglobulins are differentiated on the basis of their


A) asymmetry.
B) antigen specificity.
C) light-chain variable segments.
D) heavy-chain constant segments.
E) reactivity.

F) B) and D)
G) All of the above

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All of the following are true of the primary response of humoral immunity except that


A) it depends on antigen triggering the appropriate B cell.
B) it requires B cell differentiation into plasma cells.
C) it depends on memory B cells.
D) circulating antibodies undergo a gradual, sustained rise.
E) it peaks 1 to 2 weeks after the initial exposure.

F) A) and E)
G) B) and E)

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Immunity that is genetically determined and present at birth is called ________ immunity.


A) active
B) natural passive
C) passive
D) auto
E) innate

F) A) and D)
G) B) and D)

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The process by which the surface of a microorganism is covered with antibodies and complement, rendering it more likely to be phagocytized, is called


A) opsonization.
B) activation.
C) agglutination.
D) precipitation.
E) neutralization.

F) C) and E)
G) A) and C)

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A

The process by which antibodies bind to the antigen on the surface of cells, forming large immune complexes, is called


A) opsonization.
B) activation.
C) agglutination.
D) precipitation.
E) neutralization.

F) A) and E)
G) D) and E)

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The body's innate defenses include all of the following except


A) the skin.
B) complement.
C) interferon.
D) inflammation.
E) antibodies.

F) D) and E)
G) A) and E)

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Helper T cells do all of the following except


A) trigger B-cell division, plasma cell maturation, and antibody production.
B) provide a rapid response to a future exposure to the antigen.
C) enhance production of memory and cytotoxic T cells.
D) attract macrophages to the affected area.
E) enhance nonspecific defenses.

F) A) and E)
G) C) and D)

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The first line of cellular defense against pathogens are the


A) T cells.
B) B cells.
C) NK cells.
D) phagocytes.
E) plasma cells.

F) None of the above
G) A) and B)

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Histamine increases blood flow and vascular permeability. This would account for all of the following changes that occur during inflammation except


A) redness of the inflamed tissue.
B) chemotaxis of phagocytes.
C) heat of the inflamed tissue.
D) movement of defense proteins and cells into the interstitial space.
E) swelling of the inflamed tissue.

F) All of the above
G) None of the above

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The cells directly responsible for cellular immunity are the ________ cells.


A) dendritic
B) plasma
C) helper T
D) cytotoxic T
E) suppressor T

F) A) and B)
G) A) and C)

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Stem cells that can form all types of lymphocytes are concentrated in the


A) circulation.
B) thymus.
C) red bone marrow.
D) spleen.
E) yellow marrow.

F) C) and D)
G) D) and E)

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You are a researcher interested in studying the cytoskeleton. How can you use antibodies to locate actin-and tubulin-containing structures?

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Since those cytoskeletal components are ...

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An inflammatory response is triggered when


A) red blood cells release pyrogens.
B) T cells release interferon.
C) mast cells release histamine and heparin.
D) neutrophils phagocytize bacteria.
E) blood flow to an area increases.

F) A) and B)
G) B) and E)

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If the thymus shrank and stopped making thymosins, we would expect to see an immediate decrease in the number of


A) B lymphocytes.
B) NK cells.
C) T cells.
D) neutrophils.
E) red blood cells.

F) All of the above
G) B) and E)

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T Lymphocytes are produced and stored in all of the following except


A) the thymus.
B) lymphatic nodules.
C) lymph node organs.
D) the spleen.
E) the brain.

F) C) and D)
G) A) and E)

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E

Interferons


A) prevent viruses from leaving a cell.
B) prevent viruses from entering a cell.
C) bind to viruses and destroy them.
D) interfere with viral replication.
E) reduce macrophage chemotaxis to the infection.

F) C) and D)
G) B) and C)

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D

All of the following are true of the secondary response of humoral immunity except that it


A) depends on memory B cells.
B) results in much higher antibody titers than in the primary response.
C) results in much quicker rise in antibody titers.
D) produces more effective antibodies.
E) weakens quickly because memory B cells only survive for a year or two.

F) None of the above
G) B) and D)

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