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Inappropriate or excessive immune responses to antigens are


A) immunodeficiency diseases.
B) autoimmune diseases.
C) allergies.
D) the result of stress.
E) signs of a weak immune system.

F) C) and D)
G) A) and D)

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List and briefly describe the four general properties of adaptive immunity.

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(1) Specificity: The immune response is ...

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The end result of the classical and alternative pathways of complement activation is


A) an increase in pyrogen release.
B) release of histamine.
C) activated C3B attached to the cell wall.
D) C1 bound to two antibodies.
E) activation of properdin.

F) A) and B)
G) B) and E)

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A sensitized B cell typically is not activated until


A) it binds a helper T cell that releases cytokines.
B) it binds a cytotoxic T cell.
C) memory B cells have been cloned.
D) it has cloned plasma cells.
E) antibodies have been produced.

F) D) and E)
G) B) and E)

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All of the following are true of the thymus gland except that it


A) activates B cells.
B) reaches its greatest relative size during the second year of life.
C) involutes after puberty.
D) produces T cells.
E) lies in the anterior mediastinum.

F) A) and B)
G) A) and C)

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The complement system works closely with and complements the action of


A) interferons.
B) antibodies.
C) pyrogens.
D) phagocytes.
E) microphages.

F) D) and E)
G) B) and E)

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Milly has just received a kidney transplant and is taking cyclosporin A to help prevent graft rejection. This medication is one in a class of drugs known as ________ drugs.


A) anticoagulant
B) antibiotic
C) analgesic
D) retroviral
E) immunosuppressive

F) A) and B)
G) A) and C)

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A crime scene investigator found that a biological fluid sample contains a large amount of IgA-type antibody. This fluid is probably


A) blood.
B) lymph.
C) serum.
D) tears.
E) interstitial.

F) None of the above
G) A) and B)

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Microphages include


A) monocytes.
B) Kupffer cells.
C) neutrophils.
D) eosinophils.
E) both neutrophils and eosinophils.

F) A) and E)
G) B) and E)

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Each IgG has ________ binding sites for attachment to antigenic determinants.


A) 1
B) 2
C) 4
D) up to 8
E) as many as a 1000

F) B) and E)
G) A) and D)

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The release of endogenous pyrogen (or interleukin-1) by active macrophages would


A) cause inflammation.
B) produce a fever.
C) activate complement.
D) opsonize pathogens.
E) activate antibodies.

F) A) and B)
G) None of the above

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Figure 22-1 The Structure of a Lymph Node Figure 22-1 The Structure of a Lymph Node    Use Figure 22-1 to answer the following questions: -Identify the structure labeled  3.  A)  deep cortex B)  capsule C)  subcapsular space D)  trabeculae E)  outer cortex Use Figure 22-1 to answer the following questions: -Identify the structure labeled "3."


A) deep cortex
B) capsule
C) subcapsular space
D) trabeculae
E) outer cortex

F) A) and E)
G) A) and B)

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The movement of phagocytes through the capillary wall is called


A) chemotaxis.
B) diapedesis.
C) adherens.
D) transcytosis.
E) diffusion.

F) None of the above
G) A) and C)

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The cell that dominates the deep cortical region of a lymph node is the ________ cell.


A) B
B) T
C) plasma
D) nodule
E) NK

F) All of the above
G) C) and E)

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The merging of ________ forms the right lymphatic duct.


A) the right jugular, right subclavian, and right bronchomediastinal trunks
B) the right lumbar, right subclavian, and right bronchomediastinal trunks
C) two great vessels
D) the thoracic and mediastinal ducts
E) superior and inferior lymphatic ducts

F) A) and B)
G) A) and C)

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Lymph nodes do all of the following except


A) produce antibodies through B cells.
B) monitor the contents of lymph.
C) remove debris and pathogens from the lymph.
D) accumulate cancer cells.
E) remove excess nutrients from the lymph.

F) B) and E)
G) A) and E)

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Cytotoxic T cells can attack target cells with which of the following chemical weapons?


A) secrete strong acid
B) secrete organic solvent
C) secrete free radicals
D) secrete a cytokine that triggers apoptosis
E) secrete mutant proteins that get incorporated into the target's DNA

F) A) and C)
G) None of the above

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Plasma contains ________ special proteins that form the complement system.


A) about 3
B) exactly 10
C) roughly 18
D) exactly 25
E) more than 30

F) D) and E)
G) A) and D)

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Partial antigens that do not cause B cell activation alone are called


A) complete antigens.
B) immunoglobulins.
C) mature antigens.
D) haptens.
E) short chains.

F) A) and E)
G) A) and B)

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Cells that help regulate the immune response are ________ cells.


A) B
B) plasma
C) helper T
D) cytotoxic T
E) NK

F) B) and C)
G) B) and D)

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