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Maternal serum marker tests detect metabolites in the fetus that may be associated with specific medical conditions.

A) True
B) False

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Down syndrome is caused by


A) nondisjunction or a translocation.
B) the karyotype XXY.
C) an extra Y chromosome.
D) a missing autosome.

E) C) and D)
F) A) and B)

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The processes that pass genetic information from generation to generation are


A) mitosis and fertilization.
B) meiosis and fertilization.
C) mitosis and meiosis.
D) interactions of DNA and the environment.

E) B) and C)
F) A) and D)

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In incomplete dominance, the phenotype of a heterozygote is in between that of either homozygote.

A) True
B) False

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A human male is hemizygous for genes on the X chromosome because he has two copies of that chromosome.

A) True
B) False

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During amniocentesis


A) a needle removes cells from the fetus.
B) a piece of the placenta is snipped off and examined for abnormal cells.
C) fetal fibroblasts in amniotic fluid are cultured and a karyotype constructed.
D) blood is removed from a woman's arm and fetal cells isolated and their chromosomes karyotyped.

E) All of the above
F) A) and B)

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Chromosome abnormalities include having a number other than 46, a chromosome that has an inverted sequence, and different chromosome types that exchange parts.

A) True
B) False

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The expression of an inherited trait is the genotype and the DNA sequence is the phenotype.

A) True
B) False

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The two types of information needed to predict the inheritance pattern of a trait are


A) the way genes are distributed in meiosis and the way that they come together when sperm joins egg.
B) the health of the mother and the father.
C) the way mitosis distributes the alleles of a gene and whether those alleles are dominant or recessive.
D) the age at which the trait appears and how it affects males or females.

E) None of the above
F) A) and B)

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The two general types of chromosomes are


A) autosomes and allosomes.
B) sex chromosomes and allosomes.
C) sex chromosomes and autosomes.
D) X and Y chromosomes.

E) A) and B)
F) A) and C)

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A human cell that has 47 chromosomes is


A) monosomic.
B) euploid.
C) polyploid.
D) trisomic.

E) None of the above
F) C) and D)

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Beard growth is a sex-influenced trait.

A) True
B) False

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Different alleles of the same gene are said to be


A) homozygous.
B) heterozygous.
C) recessive.
D) dominant.

E) A) and D)
F) B) and C)

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Genes have multiple alleles that differ in DNA sequence because a gene consists of many nucleotides, each of which can be any of four types.

A) True
B) False

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Your family has a strong genetic predisposition to abnormal blood clotting and deep vein thrombosis. How does this affect or determine your chances of suffering from the same conditions? 


A) You are guaranteed to experience blood clots and deep vein thrombosis, as the genes producing such conditions are definitely in your genome and will become active at some point.
B) You don't have to worry about these conditions because genetic predisposition doesn't at all affect your chances of developing these conditions if you exercise regularly and eat healthy foods.
C) You must expect to die from such conditions if more than 4 or 5 of your relatives have also died from them, as medicine does not yet know how to stop genetic conditions from taking their course.
D) You have a higher risk of suffering from these conditions, but you can still take preventative steps to reduce the risk if you know about the genetic predisposition. You are not absolutely guaranteed to suffer deep vein thrombosis because environmental factors can be changed.

E) A) and C)
F) All of the above

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A pharmacogenetic test can reveal whether a certain drug will be effective and/or cause adverse effects in a particular person.

A) True
B) False

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Polydactyly is an example of a trait that is both ________ and variably expressive.


A) incompletely penetrant
B) pleiotropic
C) multifactorial
D) completely penetrant

E) A) and B)
F) A) and C)

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A genotype that does not affect everyone who inherits it is completely penetrant.

A) True
B) False

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The field of genetics deals only with disease.

A) True
B) False

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A gene typically has many alleles because


A) humans have many traits.
B) a chromosome has many genes.
C) a DNA sequence can vary in many ways.
D) a protein sequence can vary in many ways.

E) C) and D)
F) B) and D)

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